genetica:impute
Imputation with impute2
Very basic use:
- -g <input file> - database to input (see format below)
- -m <map> - recombination map as 1000Genome or something like this
- -int <lower> <upper> - interval to make the imputation
Input file format
From plink to impute format
First convert the binary files to .ped and .map if needed
http://pngu.mgh.harvard.edu/~purcell/plink/dataman.shtml
then you can use gtool,
http://www.well.ox.ac.uk/~cfreeman/software/gwas/gtool.html
in particular, http://www.well.ox.ac.uk/~cfreeman/software/gwas/gtool.html#PED to GEN Conversion
gtool -P --ped example/example.ped --map example/example.map --og example/out.gen --os example/out.sample
Before this some awkward work need to be done
genetica/impute.txt · Last modified: 2020/08/04 10:58 by 127.0.0.1